Upset about moving from a big city to a small town, teenager Zach Cooper (Dylan Minnette) finds a silver lining when he meets the beautiful girl, Hannah (Odeya Rush), living right next door. But every silver lining has a cloud, and Zach’s comes when he learns that Hannah has a mysterious dad who is revealed to be R. L. Stine (Jack Black), the author of the bestselling Goosebumps series. It turns out that there is a reason why Stine is so strange… he is a prisoner of his own imagination – the monsters that his books made famous are real, and Stine protects his readers by keeping them locked up in their books. When Zach unintentionally unleashes the monsters from their manuscripts and they begin to terrorize the town, it’s suddenly up to Stine, Zach, Hannah, and Zach’s friend Champ (Ryan Lee) to get all of them back in the books where they belong.
故事描述剛從大城市搬到鄉下的青少年柴克，認識了鄰居的漂亮女孩漢娜。沒多久他發現漢娜的爸爸，知名恐怖童書作者史汀行徑古怪；長期以來史汀將怪獸們監禁在書中，以避免危害人群。然而柴克和朋友卻不小心讓怪獸從書中逃出，並危害整個小鎮。史汀、漢娜與柴克要怎麼把怪獸趕回書裡呢？